gnu: Add r-birta.
* gnu/packages/bioconductor.scm (r-birta): New variable.
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@ -4577,3 +4577,32 @@ (define-public r-birewire
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the introduced randomness across the switching steps and several other
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the introduced randomness across the switching steps and several other
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routines to analyse the resulting networks and their natural projections.")
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routines to analyse the resulting networks and their natural projections.")
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(license license:gpl3)))
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(license license:gpl3)))
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(define-public r-birta
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(package
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(name "r-birta")
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(version "1.28.0")
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(source
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(origin
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(method url-fetch)
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(uri (bioconductor-uri "birta" version))
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(sha256
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(base32
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"12xjyvgmh4h0b7hi4qg50kcpb9003gnh2xyfgncb8l9mzvsbkxc2"))))
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(build-system r-build-system)
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(propagated-inputs
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`(("r-biobase" ,r-biobase)
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("r-limma" ,r-limma)
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("r-mass" ,r-mass)))
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(home-page "https://bioconductor.org/packages/birta")
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(synopsis "Bayesian inference of regulation of transcriptional activity")
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(description
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"Expression levels of mRNA molecules are regulated by different
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processes, comprising inhibition or activation by transcription factors and
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post-transcriptional degradation by microRNAs. @dfn{birta} (Bayesian
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Inference of Regulation of Transcriptional Activity) uses the regulatory
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networks of transcription factors and miRNAs together with mRNA and miRNA
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expression data to predict switches in regulatory activity between two
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conditions. A Bayesian network is used to model the regulatory structure and
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Markov-Chain-Monte-Carlo is applied to sample the activity states.")
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(license license:gpl2+)))
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