From 1a24f855c8dcb61f34b1ec7390ca90e2540c53d9 Mon Sep 17 00:00:00 2001 From: Ricardo Wurmus Date: Fri, 31 May 2019 14:40:29 +0200 Subject: [PATCH] gnu: Add r-birta. * gnu/packages/bioconductor.scm (r-birta): New variable. --- gnu/packages/bioconductor.scm | 29 +++++++++++++++++++++++++++++ 1 file changed, 29 insertions(+) diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm index 10a4079fea..5ffb7c4e3c 100644 --- a/gnu/packages/bioconductor.scm +++ b/gnu/packages/bioconductor.scm @@ -4577,3 +4577,32 @@ (define-public r-birewire the introduced randomness across the switching steps and several other routines to analyse the resulting networks and their natural projections.") (license license:gpl3))) + +(define-public r-birta + (package + (name "r-birta") + (version "1.28.0") + (source + (origin + (method url-fetch) + (uri (bioconductor-uri "birta" version)) + (sha256 + (base32 + "12xjyvgmh4h0b7hi4qg50kcpb9003gnh2xyfgncb8l9mzvsbkxc2")))) + (build-system r-build-system) + (propagated-inputs + `(("r-biobase" ,r-biobase) + ("r-limma" ,r-limma) + ("r-mass" ,r-mass))) + (home-page "https://bioconductor.org/packages/birta") + (synopsis "Bayesian inference of regulation of transcriptional activity") + (description + "Expression levels of mRNA molecules are regulated by different +processes, comprising inhibition or activation by transcription factors and +post-transcriptional degradation by microRNAs. @dfn{birta} (Bayesian +Inference of Regulation of Transcriptional Activity) uses the regulatory +networks of transcription factors and miRNAs together with mRNA and miRNA +expression data to predict switches in regulatory activity between two +conditions. A Bayesian network is used to model the regulatory structure and +Markov-Chain-Monte-Carlo is applied to sample the activity states.") + (license license:gpl2+)))