diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index c085aea45f..9651fb0261 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -20751,14 +20751,14 @@ (define-public r-cner
 (define-public r-tfbstools
   (package
     (name "r-tfbstools")
-    (version "1.38.0")
+    (version "1.40.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "TFBSTools" version))
        (sha256
         (base32
-         "136s96cmd1aq878xy9mqd4k46awywqpmm55lpvash8mv4gg02vg8"))))
+         "18msr889nygk1c3wsjxc9bv989zakkl9f1h2a6cnfy8rxhbxpvwq"))))
     (properties `((upstream-name . "TFBSTools")))
     (build-system r-build-system)
     (propagated-inputs