diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index aa3ecdb7f7..d5dc61ed33 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -2219,13 +2219,13 @@ (define-public r-decoupler
 (define-public r-deepsnv
   (package
     (name "r-deepsnv")
-    (version "1.40.0")
+    (version "1.42.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "deepSNV" version))
               (sha256
                (base32
-                "1wi6j6yb6i9fs9yszfywqz3w50mhl85dkfmr4w3phwvkf0xkn81w"))))
+                "0si1x2bi5pff1dicpqg7hv4ziq46vm7lic72724ljsclpz9bfv6q"))))
     (properties `((upstream-name . "deepSNV")))
     (build-system r-build-system)
     (propagated-inputs