diff --git a/gnu/packages/animation.scm b/gnu/packages/animation.scm
index 33fc3fcce9..4c03b78717 100644
--- a/gnu/packages/animation.scm
+++ b/gnu/packages/animation.scm
@@ -260,7 +260,7 @@ (define-public gnash
          ("python" ,python-wrapper)))
       (inputs
        `(("agg" ,agg)
-         ("atk" ,atk)
+         ("at-spi2-core" ,at-spi2-core)
          ("boost" ,boost)
          ("curl" ,curl)
          ("ffmpeg" ,ffmpeg-2.8)
diff --git a/gnu/packages/chromium.scm b/gnu/packages/chromium.scm
index 47153e3531..22e22cdbf8 100644
--- a/gnu/packages/chromium.scm
+++ b/gnu/packages/chromium.scm
@@ -898,7 +898,6 @@ (define-public ungoogled-chromium
            wayland))
     (inputs
      (list alsa-lib
-           atk
            at-spi2-core
            cups
            curl
diff --git a/gnu/packages/crates-gtk.scm b/gnu/packages/crates-gtk.scm
index 403c1f2aef..1c99c87bb6 100644
--- a/gnu/packages/crates-gtk.scm
+++ b/gnu/packages/crates-gtk.scm
@@ -60,7 +60,7 @@ (define-public rust-atk-sys-0.14
         ("rust-tempfile" ,rust-tempfile-3))))
     (native-inputs (list pkg-config))
     (inputs
-     (list atk glib))
+     (list at-spi2-core glib))
     (home-page "https://gtk-rs.org/")
     (synopsis "FFI bindings to libatk-1")
     (description "FFI bindings to libatk-1")
@@ -90,7 +90,7 @@ (define-public rust-atk-sys-0.10
         ("rust-tempfile" ,rust-tempfile-3))))
     (native-inputs (list pkg-config))
     (inputs
-     (list atk glib))))
+     (list at-spi2-core glib))))
 
 (define-public rust-atk-sys-0.9
   (package
@@ -138,7 +138,7 @@ (define-public rust-atk-0.14
        #:cargo-development-inputs
        (("rust-gir-format-check" ,rust-gir-format-check-0.1))))
     (inputs
-     (list atk glib))
+     (list at-spi2-core glib))
     (home-page "https://gtk-rs.org/")
     (synopsis "Rust bindings for the ATK library")
     (description "Rust bindings for the ATK library")
@@ -1469,7 +1469,7 @@ (define-public rust-gtk-0.14
        (("rust-gir-format-check" ,rust-gir-format-check-0.1))))
     (native-inputs (list pkg-config))
     (inputs
-     (list atk cairo glib gtk+ pango))
+     (list at-spi2-core cairo glib gtk+ pango))
     (home-page "https://gtk-rs.org/")
     (synopsis "Rust bindings for the GTK+ 3 library")
     (description "This package provides Rust bindings for the GTK+ 3 library.")
diff --git a/gnu/packages/gimp.scm b/gnu/packages/gimp.scm
index af5adb8bfd..73102e30cf 100644
--- a/gnu/packages/gimp.scm
+++ b/gnu/packages/gimp.scm
@@ -333,7 +333,7 @@ (define-public gimp
               ;; ./configure requests not to annoy upstream with packaging bugs.
               "--with-bug-report-url=https://bugs.gnu.org/guix")))
     (inputs
-     (list atk
+     (list at-spi2-core
            babl
            gegl
            gexiv2
diff --git a/gnu/packages/gnome.scm b/gnu/packages/gnome.scm
index e2ee396819..e81882b181 100644
--- a/gnu/packages/gnome.scm
+++ b/gnu/packages/gnome.scm
@@ -2704,7 +2704,7 @@ (define-public evince
            libgnome-keyring
            adwaita-icon-theme
            gdk-pixbuf
-           atk
+           at-spi2-core
            pango
            gtk+
            glib
@@ -3299,7 +3299,7 @@ (define-public glade3
           '())
       (list gtk+ libxml2)))
     (native-inputs
-     (list atk                          ;for tests
+     (list at-spi2-core                          ;for tests
            docbook-xml-4.2
            docbook-xsl
            gettext-minimal
@@ -6357,7 +6357,7 @@ (define-public clutter
            libxslt
            pkg-config))
     (propagated-inputs
-     (list atk
+     (list at-spi2-core
            cairo
            cogl
            glib
@@ -6744,7 +6744,7 @@ (define-public totem
     (inputs
      (list gtk+
            gdk-pixbuf
-           atk
+           at-spi2-core
            cairo
            dbus-glib
            xorgproto
@@ -6866,7 +6866,7 @@ (define-public rhythmbox
      ;;clutter-gtk
      ;;clutter-gst
      (list adwaita-icon-theme
-           atk
+           at-spi2-core
            bash-minimal
            brasero
            json-glib
@@ -8021,7 +8021,7 @@ (define-public mutter
      (list gsettings-desktop-schemas-next ;required by libmutter.pc
            gtk+                           ;required by libmutter.pc
            ;; mutter-clutter-1.0.pc and mutter-cogl-1.0.pc refer to these:
-           atk
+           at-spi2-core
            cairo
            eudev
            gdk-pixbuf
@@ -11646,7 +11646,7 @@ (define-public ghex
            pkg-config
            yelp-tools))
     (inputs
-     (list atk
+     (list at-spi2-core
            gtk))
     (synopsis "GNOME hexadecimal editor")
     (description "The GHex program can view and edit files in two ways:
diff --git a/gnu/packages/graphviz.scm b/gnu/packages/graphviz.scm
index aa3cee6e5b..d98041d73a 100644
--- a/gnu/packages/graphviz.scm
+++ b/gnu/packages/graphviz.scm
@@ -346,7 +346,7 @@ (define-public xdot
                `("PATH" ":" prefix
                  (,(dirname (search-input-file inputs "bin/dot"))))))))))
     (inputs
-     (list atk
+     (list at-spi2-core
            (librsvg-for-system)
            harfbuzz
            graphviz
diff --git a/gnu/packages/gtk.scm b/gnu/packages/gtk.scm
index 65854e0ba0..a19c9c372b 100644
--- a/gnu/packages/gtk.scm
+++ b/gnu/packages/gtk.scm
@@ -934,7 +934,7 @@ (define-public gtk+-2
     (build-system gnu-build-system)
     (outputs '("out" "bin" "doc" "debug"))
     (propagated-inputs
-     (list atk
+     (list at-spi2-core
            cairo
            glib
            (librsvg-for-system)
@@ -1030,8 +1030,7 @@ (define-public gtk+
        (patches (search-patches "gtk3-respect-GUIX_GTK3_PATH.patch"
                                 "gtk3-respect-GUIX_GTK3_IM_MODULE_FILE.patch"))))
     (propagated-inputs
-     (list atk
-           at-spi2-core
+     (list at-spi2-core
            cairo
            fribidi
            fontconfig
@@ -1587,7 +1586,7 @@ (define-public guile-gnome
     (build-system gnu-build-system)
     (native-inputs
      (list pkg-config
-           atk
+           at-spi2-core
            ;;("corba" ,corba) ; not packaged yet
            gconf
            gobject-introspection
@@ -1797,7 +1796,7 @@ (define-public atkmm
        ("python" ,python)
        ("xsltproc" ,libxslt)))
     (propagated-inputs
-     (list glibmm atk))
+     (list glibmm at-spi2-core))
     (synopsis "C++ bindings for ATK")
     (description "ATKmm is the C++ binding for the ATK library.")
     (home-page "https://wiki.gnome.org/Accessibility")
diff --git a/gnu/packages/mate.scm b/gnu/packages/mate.scm
index 2f38946fe1..4874aaf7f9 100644
--- a/gnu/packages/mate.scm
+++ b/gnu/packages/mate.scm
@@ -521,7 +521,7 @@ (define-public mate-applets
            docbook-xml
            gobject-introspection))
     (inputs
-     (list atk
+     (list at-spi2-core
            dbus
            dbus-glib
            glib
@@ -732,7 +732,7 @@ (define-public atril
        ("xmllint" ,libxml2)
        ("zlib" ,zlib)))
     (inputs
-     `(("atk" ,atk)
+     `(("at-spi2-core" ,at-spi2-core)
        ("cairo" ,cairo)
        ("caja" ,caja)
        ("dconf" ,dconf)
@@ -921,7 +921,7 @@ (define-public mate-control-center
            xmodmap
            gobject-introspection))
     (inputs
-     `(("atk" ,atk)
+     `(("at-spi2-core" ,at-spi2-core)
        ("cairo" ,cairo)
        ("caja" ,caja)
        ("dconf" ,dconf)
@@ -1061,7 +1061,7 @@ (define-public mate-calc
     (native-inputs
      (list gettext-minimal intltool pkg-config yelp-tools))
     (inputs
-     (list atk
+     (list at-spi2-core
            glib
            gtk+
            libxml2
@@ -1228,7 +1228,7 @@ (define-public mate-utils
            xorgproto
            yelp-tools))
     (inputs
-     (list atk
+     (list at-spi2-core
            cairo
            glib
            gtk+
@@ -1277,7 +1277,7 @@ (define-public eom
            pkg-config
            yelp-tools))
     (inputs
-     (list atk
+     (list at-spi2-core
            cairo
            dconf
            dbus
@@ -1382,7 +1382,7 @@ (define-public pluma
        ("pkg-config" ,pkg-config)
        ("yelp-tools" ,yelp-tools)))
     (inputs
-     (list atk
+     (list at-spi2-core
            cairo
            enchant-1.6
            glib
diff --git a/gnu/packages/messaging.scm b/gnu/packages/messaging.scm
index bbd1743cac..1cef8d4811 100644
--- a/gnu/packages/messaging.scm
+++ b/gnu/packages/messaging.scm
@@ -1373,7 +1373,7 @@ (define-public dino
            vala))
     (inputs
      (list adwaita-icon-theme
-           atk
+           at-spi2-core
            bash-minimal
            cairo
            librsvg
diff --git a/gnu/packages/qt.scm b/gnu/packages/qt.scm
index 0208312bd5..407ae1dd5d 100644
--- a/gnu/packages/qt.scm
+++ b/gnu/packages/qt.scm
@@ -2640,7 +2640,7 @@ (define-public qtwebengine-5
            ruby))
     (inputs
      (list alsa-lib
-           atk
+           at-spi2-core
            cups-minimal
            curl
            dbus
diff --git a/gnu/packages/rust-apps.scm b/gnu/packages/rust-apps.scm
index b8cb06af64..5ec82009af 100644
--- a/gnu/packages/rust-apps.scm
+++ b/gnu/packages/rust-apps.scm
@@ -177,7 +177,7 @@ (define-public alfis
     (native-inputs
      (list pkg-config))
     (inputs
-     (list atk
+     (list at-spi2-core
            gtk
            glib
            pango
diff --git a/gnu/packages/vim.scm b/gnu/packages/vim.scm
index 6baf10915a..d555194d0b 100644
--- a/gnu/packages/vim.scm
+++ b/gnu/packages/vim.scm
@@ -243,7 +243,7 @@ (define-public vim-full
        (prepend pkg-config xorg-server-for-tests)))
     (inputs
      `(("acl" ,acl)
-       ("atk" ,atk)
+       ("at-spi2-core" ,at-spi2-core)
        ("attr" ,attr)
        ("cairo" ,cairo)
        ("fontconfig" ,fontconfig)
diff --git a/gnu/packages/vnc.scm b/gnu/packages/vnc.scm
index fc272ae621..37c9ae0619 100644
--- a/gnu/packages/vnc.scm
+++ b/gnu/packages/vnc.scm
@@ -123,7 +123,7 @@ (define-public remmina
            pkg-config))
     (inputs
      (list libappindicator
-           atk
+           at-spi2-core
            avahi
            cairo
            cups
diff --git a/gnu/packages/web.scm b/gnu/packages/web.scm
index b1d6e8768b..24f5021889 100644
--- a/gnu/packages/web.scm
+++ b/gnu/packages/web.scm
@@ -6628,7 +6628,7 @@ (define-public castor
     (native-inputs
      (list pkg-config))
     (inputs
-     (list atk
+     (list at-spi2-core
            cairo
            gdk-pixbuf
            gtk+