diff --git a/gnu/packages/fontutils.scm b/gnu/packages/fontutils.scm
index 9b7f1ac879..f80130a565 100644
--- a/gnu/packages/fontutils.scm
+++ b/gnu/packages/fontutils.scm
@@ -2,7 +2,7 @@
 ;;; Copyright © 2013, 2014, 2015 Andreas Enge <andreas@enge.fr>
 ;;; Copyright © 2014, 2016 Eric Bavier <bavier@member.fsf.org>
 ;;; Copyright © 2016 Mark H Weaver <mhw@netris.org>
-;;; Copyright © 2016, 2017, 2020 Efraim Flashner <efraim@flashner.co.il>
+;;; Copyright © 2016, 2017, 2020, 2022 Efraim Flashner <efraim@flashner.co.il>
 ;;; Copyright © 2017 Rene Saavedra <rennes@openmailbox.org>
 ;;; Copyright © 2017 Leo Famulari <leo@famulari.name>
 ;;; Copyright © 2017 Nikita <nikita@n0.is>
@@ -227,7 +227,10 @@ (define-public python-afdko
               (when tests?
                 (setenv "HOME" "/tmp")
                 (invoke "pytest" "-vv" "--dist" "loadfile" "-n"
-                        (number->string (parallel-job-count))))))
+                        (number->string (parallel-job-count))
+                        ;; This test is known to fail on multiple architectures.
+                        ;; https://github.com/adobe-type-tools/afdko/issues/1163
+                        "-k not test_type1mm_inputs"))))
           (add-after 'check 'wrap
             (assoc-ref %standard-phases 'wrap))
           (add-before 'wrap 'wrap-PATH