diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 02e417d98d..1b89d751fe 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -4211,14 +4211,14 @@ (define-public r-fastseg
 (define-public r-gage
   (package
     (name "r-gage")
-    (version "2.46.0")
+    (version "2.46.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "gage" version))
        (sha256
         (base32
-         "03hx188h98qrbpjlf8v9sg2vqyfv49rp4c18ir11pg6hwqqrxh7b"))))
+         "01y04jcy7a9fksyhj0nq37n1inkrpqf4qv117lflvipbx0dsw4gl"))))
     (build-system r-build-system)
     (propagated-inputs
      (list r-annotationdbi r-go-db r-graph r-keggrest))