diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 1e1597960d..da5ccf4efb 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -3731,14 +3731,14 @@ (define-public r-heatplus
 (define-public r-gosemsim
   (package
     (name "r-gosemsim")
-    (version "2.14.2")
+    (version "2.16.1")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GOSemSim" version))
        (sha256
         (base32
-         "02r7m1x6g8bb7q8l0hpvakdzdv5v1nplhx5lbiy798a7c3xg895b"))))
+         "1hk1626172scja2gr6axy98czblz0zljiqgqaknsv2xj6frhxcgs"))))
     (properties `((upstream-name . "GOSemSim")))
     (build-system r-build-system)
     (propagated-inputs