diff --git a/gnu/packages/python-web.scm b/gnu/packages/python-web.scm
index 8b6d454780..7636931091 100644
--- a/gnu/packages/python-web.scm
+++ b/gnu/packages/python-web.scm
@@ -86,6 +86,7 @@ (define-module (gnu packages python-web)
   #:use-module (gnu packages libevent)
   #:use-module (gnu packages libffi)
   #:use-module (gnu packages node)
+  #:use-module (gnu packages openstack)
   #:use-module (gnu packages pcre)
   #:use-module (gnu packages pkg-config)
   #:use-module (gnu packages python)
@@ -6389,53 +6390,55 @@ (define-public python-sanic-testing
 (define-public python-sanic
   (package
     (name "python-sanic")
-    (version "20.12.4")
+    ;; We provide the latest LTS version of python-sanic.
+    (version "21.12.1")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "sanic" version))
        (sha256
         (base32
-         "0axfc151s7nrykzypzciyvkxxrs5ayx8kxv4r620hjb9w3jjhfnp"))))
+         "0b8mcd1q9qkwcv2qz8nlyaacs0bp7a1l31sdq2m8hhkxykzfq5bg"))))
     (build-system python-build-system)
     (arguments
-     '(#:phases
-       (modify-phases %standard-phases
-         (add-after 'unpack 'use-recent-pytest
-           ;; Allow using recent dependencies.
-           (lambda* (#:key inputs #:allow-other-keys)
-             (substitute* "setup.py"
-               (("pytest==5.2.1") "pytest")
-               (("multidict>=5.0,<6.0") "multidict")
-               (("httpx==0\\.15\\.4") "httpx"))
-             #t))
-         (replace 'check
-           (lambda* (#:key inputs outputs #:allow-other-keys)
-             (add-installed-pythonpath inputs outputs)
-             (invoke "pytest" "-vv" "./tests" "-k"
-                     (string-append "not test_zero_downtime "
-                                    "and not test_gunicorn_worker "
-                                    "and not test_logo_")))))))
+      (list
+       #:phases
+         #~(modify-phases %standard-phases
+           (replace 'check
+             (lambda* (#:key tests? #:allow-other-keys)
+               (when tests?
+                 (invoke "pytest" "-vv" "./tests" "-k"
+                         (string-append
+                           ;; PyPi sources lack examples module.
+                           "not test_gunicorn_"
+                           ;; Does not expect brotli and reordered headers.
+                           " and not test_raw_headers"
+                           ;; These look like buggy testcases.
+                           " and not test_zero_downtime"
+                           " and not test_non_default_uvloop_config_raises_warning"
+                           " and not test_listeners_triggered"
+                           " and not test_keep_alive_connection_context"
+                           " and not test_keep_alive_client_timeout"))))))))
     (propagated-inputs
      (list python-aiofiles
            python-httptools
-           python-httpx
            python-multidict
+           python-sanic-routing
            python-ujson
            python-uvloop
            python-websockets))
     (native-inputs
      (list gunicorn
+           python-bandit
            python-beautifulsoup4
-           python-hstspreload
-           python-httpcore
+           python-chardet
+           python-isort
            python-pytest
-           python-pytest-cov
            python-pytest-benchmark
            python-pytest-sanic
            python-pytest-sugar
            python-pytest-asyncio
-           python-urllib3
+           python-sanic-testing
            python-uvicorn))
     (home-page
      "https://github.com/sanic-org/sanic/")