diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 371c13e121..9dcc9c8a38 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -14246,7 +14246,12 @@ (define-public nanopolish
                (recursive? #t)))
          (file-name (git-file-name name version))
          (sha256
-          (base32 "09j5gz57yr9i34a27vbl72i4g8syv2zzgmsfyjq02yshmnrvkjs6"))))
+          (base32 "09j5gz57yr9i34a27vbl72i4g8syv2zzgmsfyjq02yshmnrvkjs6"))
+         (modules '((guix build utils)))
+         (snippet
+          '(begin
+             (delete-file-recursively "htslib")
+             #t))))
       (build-system gnu-build-system)
       (arguments
        `(#:make-flags