diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 1988de309c..3884b72738 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -2701,29 +2701,32 @@ (define-public r-ebseq
 (define-public r-karyoploter
   (package
     (name "r-karyoploter")
-    (version "1.12.4")
+    (version "1.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "karyoploteR" version))
               (sha256
                (base32
-                "03jmfgmw35hrgn3pc5lq6pblzhfx9fp4l6dx50rp303lr7kjxp9v"))))
+                "0h0gk4xd95k5phy6qcsv7j931d7gk3p24i2fg4mz5dsk110lpifs"))))
     (build-system r-build-system)
     (propagated-inputs
-     `(("r-regioner" ,r-regioner)
-       ("r-genomicranges" ,r-genomicranges)
-       ("r-iranges" ,r-iranges)
-       ("r-rsamtools" ,r-rsamtools)
-       ("r-memoise" ,r-memoise)
-       ("r-rtracklayer" ,r-rtracklayer)
-       ("r-genomeinfodb" ,r-genomeinfodb)
-       ("r-s4vectors" ,r-s4vectors)
+     `(("r-annotationdbi" ,r-annotationdbi)
+       ("r-bamsignals" ,r-bamsignals)
+       ("r-bezier" ,r-bezier)
        ("r-biovizbase" ,r-biovizbase)
        ("r-digest" ,r-digest)
-       ("r-bezier" ,r-bezier)
-       ("r-bamsignals" ,r-bamsignals)
-       ("r-annotationdbi" ,r-annotationdbi)
+       ("r-genomeinfodb" ,r-genomeinfodb)
+       ("r-genomicfeatures" ,r-genomicfeatures)
+       ("r-genomicranges" ,r-genomicranges)
+       ("r-iranges" ,r-iranges)
+       ("r-memoise" ,r-memoise)
+       ("r-regioner" ,r-regioner)
+       ("r-rsamtools" ,r-rsamtools)
+       ("r-rtracklayer" ,r-rtracklayer)
+       ("r-s4vectors" ,r-s4vectors)
        ("r-variantannotation" ,r-variantannotation)))
+    (native-inputs
+     `(("r-knitr" ,r-knitr)))
     (home-page "https://bioconductor.org/packages/karyoploteR/")
     (synopsis "Plot customizable linear genomes displaying arbitrary data")
     (description "This package creates karyotype plots of arbitrary genomes and