diff --git a/gnu/packages/python-crypto.scm b/gnu/packages/python-crypto.scm
index bad774aa03..7084c3a4ec 100644
--- a/gnu/packages/python-crypto.scm
+++ b/gnu/packages/python-crypto.scm
@@ -61,6 +61,7 @@ (define-module (gnu packages python-crypto)
   #:use-module (gnu packages swig)
   #:use-module (gnu packages time)
   #:use-module (gnu packages tls)
+  #:use-module (gnu packages xml)
   #:use-module ((guix licenses) #:prefix license:)
   #:use-module (srfi srfi-1))
 
@@ -1060,6 +1061,53 @@ (define-public python2-m2crypto
              (propagated-inputs
               `(("python2-typing" ,python2-typing))))))
 
+(define-public python-pykeepass
+  (package
+    (name "python-pykeepass")
+    (version "3.2.0")
+    (source
+     (origin
+       (method git-fetch)
+       ;; Source tarball on PyPI doesn't include tests.
+       (uri (git-reference
+             (url "https://github.com/libkeepass/pykeepass")
+             (commit version)))
+       (file-name (git-file-name name version))
+       (sha256
+        (base32 "1wxbfpy7467mlnfsvmh685fhfnq4fki9y7yc9cylp30r5n3hisaj"))))
+    (build-system python-build-system)
+    (arguments
+     `(#:phases
+       (modify-phases %standard-phases
+         (add-after 'unpack 'make-kdbx-writable
+           ;; Tests have to write to the .kdbx files in the test directory.
+           (lambda _
+             (with-directory-excursion "tests"
+               (for-each make-file-writable (find-files "."))
+               #t)))
+         (add-before 'build 'patch-requirements
+           (lambda _
+             ;; Update requirements from dependency==version
+             ;; to dependency>=version.
+             (substitute* "setup.py"
+               (("==") ">="))
+             #t)))))
+    (propagated-inputs
+     `(("python-argon2-cffi" ,python-argon2-cffi)
+       ("python-construct" ,python-construct)
+       ("python-dateutil" ,python-dateutil)
+       ("python-future" ,python-future)
+       ("python-lxml" ,python-lxml)
+       ("python-pycryptodome" ,python-pycryptodome)))
+    (home-page "https://github.com/libkeepass/pykeepass")
+    (synopsis "Python library to interact with keepass databases")
+    (description
+     "This library allows you to write entries to a KeePass database.  It
+supports KDBX3 and KDBX4.")
+    ;; There are no copyright headers in the source code.  The LICENSE file
+    ;; indicates GPL3.
+    (license license:gpl3+)))
+
 (define-public python-pylibscrypt
   (package
     (name "python-pylibscrypt")