diff --git a/gnu/local.mk b/gnu/local.mk
index b3d6054b50..57346cc2ef 100644
--- a/gnu/local.mk
+++ b/gnu/local.mk
@@ -1027,7 +1027,6 @@ dist_patch_DATA =						\
   %D%/packages/patches/guile-2.2-skip-oom-test.patch            \
   %D%/packages/patches/guile-default-utf8.patch			\
   %D%/packages/patches/guile-gdbm-ffi-support-gdbm-1.14.patch	\
-  %D%/packages/patches/guile-json-cross.patch			\
   %D%/packages/patches/guile-linux-syscalls.patch		\
   %D%/packages/patches/guile-present-coding.patch		\
   %D%/packages/patches/guile-relocatable.patch			\
diff --git a/gnu/packages/guile.scm b/gnu/packages/guile.scm
index a262553ba1..8665e2ef79 100644
--- a/gnu/packages/guile.scm
+++ b/gnu/packages/guile.scm
@@ -532,26 +532,17 @@ (define-public guile-json-3
   (package
     (inherit guile-json-1)
     (name "guile-json")
-    (version "3.2.0")
+    (version "3.5.0")
     (source (origin
               (method url-fetch)
               (uri (string-append "mirror://savannah/guile-json/guile-json-"
                                   version ".tar.gz"))
-              (patches (search-patches "guile-json-cross.patch"))
               (sha256
                (base32
-                "14m6b6g2maw0mkvfm4x63rqb54vgbpn1gcqs715ijw4bikfzlqfz"))))
-    (native-inputs `(("autoconf" ,autoconf)
-                     ("automake" ,automake)
-                     ("pkg-config" ,pkg-config)
+                "0nj0684qgh6ppkbdyxqfyjwsv2qbyairxpi8fzrhsi3xnc7jn4im"))))
+    (native-inputs `(("pkg-config" ,pkg-config)
                      ("guile" ,guile-3.0)))
-    (inputs `(("guile" ,guile-3.0)))
-    (arguments
-     `(#:phases (modify-phases %standard-phases
-                  (add-after 'unpack 'remove-configure
-                    (lambda _
-                      (delete-file "configure")
-                      #t)))))))
+    (inputs `(("guile" ,guile-3.0)))))
 
 (define-public guile2.2-json
   (package-for-guile-2.2 guile-json-3))
diff --git a/gnu/packages/patches/guile-json-cross.patch b/gnu/packages/patches/guile-json-cross.patch
deleted file mode 100644
index b9081f3df2..0000000000
--- a/gnu/packages/patches/guile-json-cross.patch
+++ /dev/null
@@ -1,54 +0,0 @@
-Patch accepted upstream.
-
-From 9bbe0d78391c6dbe0316aa56a105d1966fddc9f0 Mon Sep 17 00:00:00 2001
-From: Jan Nieuwenhuizen <janneke@gnu.org>
-Date: Wed, 4 Mar 2020 11:17:02 +0100
-Subject: [PATCH] build: Support cross building.
-
-* configure.ac: Add AC_CANONICAL_HOST to get host.
-* Makefile.am (.scm.go): Set it as target.
-* json/Makefile.am (.scm.go): Likewise.
----
- Makefile.am      | 2 +-
- configure.ac     | 1 +
- json/Makefile.am | 2 +-
- 3 files changed, 3 insertions(+), 2 deletions(-)
-
-diff --git a/Makefile.am b/Makefile.am
-index 996f18b..1823a3f 100644
---- a/Makefile.am
-+++ b/Makefile.am
-@@ -42,7 +42,7 @@ nobase_nodist_obj_DATA = $(GOBJECTS)
- GUILE_WARNINGS = -Wunbound-variable -Warity-mismatch -Wformat
- SUFFIXES = .scm .go
- .scm.go:
--	$(top_builddir)/env $(GUILD) compile $(GUILE_WARNINGS) -o "$@" "$<"
-+	$(top_builddir)/env $(GUILD) compile --target="$(host)" $(GUILE_WARNINGS) -o "$@" "$<"
- 
- SOURCES = json.scm
- 
-diff --git a/configure.ac b/configure.ac
-index fbc1aff..937dcf7 100644
---- a/configure.ac
-+++ b/configure.ac
-@@ -25,6 +25,7 @@ AC_CONFIG_SRCDIR(json.scm)
- AC_CONFIG_AUX_DIR([build-aux])
- AM_INIT_AUTOMAKE([color-tests -Wall -Wno-portability])
- AM_SILENT_RULES([yes])
-+AC_CANONICAL_HOST
- 
- dnl We require pkg.m4 (from pkg-config) and guile.m4.
- dnl Make sure they are available.
-diff --git a/json/Makefile.am b/json/Makefile.am
-index adf5972..103b867 100644
---- a/json/Makefile.am
-+++ b/json/Makefile.am
-@@ -36,4 +36,4 @@ CLEANFILES = $(GOBJECTS)
- GUILE_WARNINGS = -Wunbound-variable -Warity-mismatch -Wformat
- SUFFIXES = .scm .go
- .scm.go:
--	$(top_builddir)/env $(GUILD) compile $(GUILE_WARNINGS) -o "$@" "$<"
-+	$(top_builddir)/env $(GUILD) compile --target="$(host)" $(GUILE_WARNINGS) -o "$@" "$<"
--- 
-2.26.0
-