diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index 10dc0b232b..ea616a2cbd 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -6688,14 +6688,14 @@ (define-public r-cistopic
 (define-public r-genie3
   (package
     (name "r-genie3")
-    (version "1.10.0")
+    (version "1.12.0")
     (source
      (origin
        (method url-fetch)
        (uri (bioconductor-uri "GENIE3" version))
        (sha256
         (base32
-         "1bsm0gxracsyg1wnaw3whvskghfpbgbm9navr8wdmxj2hjp3dqs7"))))
+         "1z7qkv0cgdx2plhc7xdz6s7vwdjhzcdadi35wg3fl6xpids5njf5"))))
     (properties `((upstream-name . "GENIE3")))
     (build-system r-build-system)
     (propagated-inputs `(("r-reshape2" ,r-reshape2)))