diff --git a/gnu/packages/python.scm b/gnu/packages/python.scm
index 98189c1d49..abf4ec6b7d 100644
--- a/gnu/packages/python.scm
+++ b/gnu/packages/python.scm
@@ -6751,7 +6751,7 @@ (define-public python-ly
 (define-public python-appdirs
   (package
     (name "python-appdirs")
-    (version "1.4.0")
+    (version "1.4.3")
     (source
       (origin
         (method url-fetch)
@@ -6761,7 +6761,7 @@ (define-public python-appdirs
                ".tar.gz"))
         (sha256
           (base32
-            "1iddva7v3fq0aqzsahkazxr7vpw28mqcrsy818z4wyiqnkplbhlg"))))
+            "14id6wxi12lgyw0mg3bcfnf888ad07jz9yj46gfzhn186z8rcn4y"))))
     (build-system python-build-system)
     (home-page "http://github.com/ActiveState/appdirs")
     (synopsis