diff --git a/gnu/packages/python-crypto.scm b/gnu/packages/python-crypto.scm
index 1c7640ac5f..861715b569 100644
--- a/gnu/packages/python-crypto.scm
+++ b/gnu/packages/python-crypto.scm
@@ -362,14 +362,14 @@ (define-public python2-certifi
 (define-public python-cryptography-vectors
   (package
     (name "python-cryptography-vectors")
-    (version "2.3.1")
+    (version "2.4.2")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "cryptography_vectors" version))
        (sha256
         (base32
-         "0ijdck30p7jv8a0zwv8b7d30ciqrmmps62lm63l4k776vihrnkdz"))))
+         "013qx2hz0jv79yzfzpn0r2kk33i5qy3sdnzgwiv5779d18snblwi"))))
     (build-system python-build-system)
     (home-page "https://github.com/pyca/cryptography")
     (synopsis "Test vectors for the cryptography package")
@@ -384,14 +384,14 @@ (define-public python2-cryptography-vectors
 (define-public python-cryptography
   (package
     (name "python-cryptography")
-    (version "2.3.1")
+    (version "2.4.2")
     (source
      (origin
        (method url-fetch)
        (uri (pypi-uri "cryptography" version))
        (sha256
         (base32
-         "1mnzf168vlxirq7fw9dm9zbvma7z8phc9cl5bffw5916m0y1244d"))))
+         "1pc60dksi9w9mshl6cvn7gdjazbp3pmydy3qp9wgy5wzd8n0b9h5"))))
     (build-system python-build-system)
     (inputs
      `(("openssl" ,openssl)))