diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 2d76a81339..f34acd124d 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -4859,6 +4859,8 @@ (define-public infernal
 structure consensus, so in many cases, it is more capable of identifying RNA
 homologs that conserve their secondary structure more than their primary
 sequence.")
+    ;; Infernal 1.1.2 requires VMX or SSE capability for parallel instructions.
+    (supported-systems '("i686-linux" "x86_64-linux"))
     (license license:bsd-3)))
 
 (define-public r-vegan