diff --git a/gnu/packages/bioconductor.scm b/gnu/packages/bioconductor.scm
index e48aca38fa..b7301b548d 100644
--- a/gnu/packages/bioconductor.scm
+++ b/gnu/packages/bioconductor.scm
@@ -6590,13 +6590,13 @@ (define-public r-rhdf5filters
 (define-public r-rsamtools
   (package
     (name "r-rsamtools")
-    (version "2.12.0")
+    (version "2.14.0")
     (source (origin
               (method url-fetch)
               (uri (bioconductor-uri "Rsamtools" version))
               (sha256
                (base32
-                "1wll703if12qrn0d11ljwf7rqhs4lb27fzyyz1hqwvzn3v361s10"))))
+                "0wd4hsn19msz0fkwfq7gvi97vlfpsbzzw3rjj4b6z7s5a83zir2z"))))
     (properties
      `((upstream-name . "Rsamtools")))
     (build-system r-build-system)