diff --git a/gnu/packages/chemistry.scm b/gnu/packages/chemistry.scm
index e7b061515b..69cfed454a 100644
--- a/gnu/packages/chemistry.scm
+++ b/gnu/packages/chemistry.scm
@@ -161,15 +161,16 @@ (define-public domainfinder
 (define-public inchi
   (package
     (name "inchi")
-    (version "1.05")
+    ;; Update the inchi-doc native input when updating inchi.
+    (version "1.06")
     (source (origin
               (method url-fetch)
-              (uri (string-append "http://www.inchi-trust.org/download/"
+              (uri (string-append "https://www.inchi-trust.org/download/"
                                   (string-join (string-split version #\.) "")
                                   "/INCHI-1-SRC.zip"))
               (sha256
                (base32
-                "081pcjx1z5jm23fs1pl2r3bccia0ww8wfkzcjpb7byhn7b513hsa"))
+                "1zbygqn0443p0gxwr4kx3m1bkqaj8x9hrpch3s41py7jq08f6x28"))
               (file-name (string-append name "-" version ".zip"))))
     (build-system gnu-build-system)
     (arguments
@@ -222,7 +223,7 @@ (define-public inchi
                                   "/INCHI-1-DOC.zip"))
            (sha256
             (base32
-             "1id1qb2y4lwsiw91qr2yqpn6kxbwjwhjk0hb2rwk4fxhdqib6da6"))
+             "1kyda09i9p89xfq90ninwi7w13k1w3ljpl4gqdhpfhi5g8fgxx7f"))
            (file-name (string-append name "-" version ".zip"))))))
     (home-page "https://www.inchi-trust.org")
     (synopsis "Utility for manipulating machine-readable chemical structures")