diff --git a/gnu/packages/bioinformatics.scm b/gnu/packages/bioinformatics.scm
index 58cee5cbbe..28b6cd318b 100644
--- a/gnu/packages/bioinformatics.scm
+++ b/gnu/packages/bioinformatics.scm
@@ -281,7 +281,8 @@ (define-public bamtools
             (setenv "LDFLAGS"
                     (string-append
                      "-Wl,-rpath="
-                     (assoc-ref outputs "out") "/lib/bamtools")))))))
+                     (assoc-ref outputs "out") "/lib/bamtools"))
+            #t)))))
     (inputs `(("zlib" ,zlib)))
     (home-page "https://github.com/pezmaster31/bamtools")
     (synopsis "C++ API and command-line toolkit for working with BAM data")
@@ -496,7 +497,8 @@ (define-public ribotaper
                 '("create_annotations_files.bash"
                   "create_metaplots.bash"
                   "Ribotaper_ORF_find.sh"
-                  "Ribotaper.sh"))))))))
+                  "Ribotaper.sh")))
+             #t)))))
     (inputs
      `(("bedtools" ,bedtools-2.18)
        ("samtools" ,samtools-0.1)
@@ -591,7 +593,8 @@ (define-public bioawk
                     (man (string-append out "/share/man/man1")))
                (mkdir-p man)
                (copy-file "awk.1" (string-append man "/bioawk.1"))
-               (install-file "bioawk" bin)))))))
+               (install-file "bioawk" bin))
+             #t)))))
     (home-page "https://github.com/lh3/bioawk")
     (synopsis "AWK with bioinformatics extensions")
     (description "Bioawk is an extension to Brian Kernighan's awk, adding the
@@ -1811,7 +1814,8 @@ (define-public codingquarry
                (copy-recursively "QuarryFiles"
                                  (string-append out "/QuarryFiles"))
                (install-file "CodingQuarry" bin)
-               (install-file "CufflinksGTF_to_CodingQuarryGFF3.py" bin)))))))
+               (install-file "CufflinksGTF_to_CodingQuarryGFF3.py" bin))
+             #t)))))
     (inputs `(("openmpi" ,openmpi)))
     (native-search-paths
      (list (search-path-specification
@@ -2727,7 +2731,8 @@ (define-public fraggenescan
                     (share (string-append out "/share/fraggenescan/train")))
                (install-file "run_FragGeneScan.pl" bin)
                (install-file "FragGeneScan" bin)
-               (copy-recursively "train" share))))
+               (copy-recursively "train" share))
+             #t))
          (delete 'check)
          (add-after 'install 'post-install-check
            ;; In lieu of 'make check', run one of the examples and check the
@@ -4153,7 +4158,8 @@ (define-public minced
                      "#!" (assoc-ref inputs "bash") "/bin/sh\n\n"
                      (assoc-ref inputs "jre") "/bin/java -jar "
                      bin "/minced.jar \"$@\"\n"))))
-               (chmod wrapper #o555)))))))
+               (chmod wrapper #o555))
+             #t)))))
     (native-inputs
      `(("jdk" ,icedtea "jdk")))
     (inputs
@@ -4408,7 +4414,7 @@ (define pplacer-scripts
        #:phases
        (modify-phases %standard-phases
          (add-after 'unpack 'enter-scripts-dir
-           (lambda _ (chdir "scripts")))
+           (lambda _ (chdir "scripts") #t))
          (replace 'check
            (lambda _ (invoke "python" "-m" "unittest" "discover" "-v") #t))
          (add-after 'install 'wrap-executables
@@ -6019,7 +6025,8 @@ (define-public star
            (lambda _
              (substitute* "Makefile"
                (("(COMPILATION_TIME_PLACE=\")(.*)(\")" _ pre mid post)
-                (string-append pre "Built with Guix" post)))))
+                (string-append pre "Built with Guix" post)))
+             #t))
          (add-after 'enter-source-dir 'do-not-use-bundled-htslib
            (lambda _
              (substitute* "Makefile"
@@ -6103,7 +6110,8 @@ (define-public subread
            (lambda* (#:key outputs #:allow-other-keys)
              (let ((bin (string-append (assoc-ref outputs "out") "/bin/")))
                (mkdir-p bin)
-               (copy-recursively "../bin" bin))))
+               (copy-recursively "../bin" bin))
+             #t))
          ;; no "configure" script
          (delete 'configure))))
     (inputs `(("zlib" ,zlib)))
@@ -12006,11 +12014,13 @@ (define-public sailfish
          (add-after 'unpack 'do-not-look-for-boost
            (lambda* (#:key inputs #:allow-other-keys)
              (substitute* "CMakeLists.txt"
-               (("find_package\\(Boost 1\\.53\\.0") "#"))))
+               (("find_package\\(Boost 1\\.53\\.0") "#"))
+             #t))
          (add-after 'unpack 'do-not-assign-to-macro
            (lambda _
              (substitute* "include/spdlog/details/format.cc"
-               (("const unsigned CHAR_WIDTH = 1;") ""))))
+               (("const unsigned CHAR_WIDTH = 1;") ""))
+             #t))
          (add-after 'unpack 'prepare-rapmap
            (lambda* (#:key inputs #:allow-other-keys)
              (let ((src "external/install/src/rapmap/")
@@ -12026,7 +12036,8 @@ (define-public sailfish
                (for-each (lambda (file)
                            (install-file file src))
                          (find-files "/tmp/rapmap/src" "\\.(c|cpp)"))
-               (copy-recursively "/tmp/rapmap/include" include))))
+               (copy-recursively "/tmp/rapmap/include" include))
+             #t))
          (add-after 'unpack 'use-system-libraries
            (lambda* (#:key inputs #:allow-other-keys)
              (substitute* '("src/SailfishIndexer.cpp"
@@ -12066,7 +12077,8 @@ (define-public sailfish
                      (string-append (getenv "CPLUS_INCLUDE_PATH")
                                     ":"
                                     (assoc-ref inputs "eigen")
-                                    "/include/eigen3")))))))
+                                    "/include/eigen3"))
+             #t)))))
     (inputs
      `(("boost" ,boost)
        ("eigen" ,eigen)
@@ -12252,11 +12264,13 @@ (define-public salmon
          (add-after 'unpack 'do-not-look-for-boost
            (lambda* (#:key inputs #:allow-other-keys)
              (substitute* "CMakeLists.txt"
-               (("find_package\\(Boost 1\\.53\\.0") "#"))))
+               (("find_package\\(Boost 1\\.53\\.0") "#"))
+             #t))
          (add-after 'unpack 'do-not-phone-home
            (lambda _
              (substitute* "src/Salmon.cpp"
-               (("getVersionMessage\\(\\)") "\"\""))))
+               (("getVersionMessage\\(\\)") "\"\""))
+             #t))
          (add-after 'unpack 'prepare-rapmap
            (lambda* (#:key inputs #:allow-other-keys)
              (let ((src "external/install/src/rapmap/")
@@ -12273,7 +12287,8 @@ (define-public salmon
                                        "external/install/include/rapmap/concurrentqueue.h"
                                        "external/install/include/rapmap/FastxParserThreadUtils.hpp"
                                        "external/install/src/rapmap/FastxParser.cpp"
-                                       "external/install/src/rapmap/xxhash.c")))))
+                                       "external/install/src/rapmap/xxhash.c")))
+             #t))
          (add-after 'unpack 'use-system-libraries
            (lambda* (#:key inputs #:allow-other-keys)
              (substitute* "src/CMakeLists.txt"