diff --git a/guix/self.scm b/guix/self.scm
index 126116e08a..ecf846490f 100644
--- a/guix/self.scm
+++ b/guix/self.scm
@@ -911,7 +911,11 @@ (define (shorten version)
         version))
 
   (define guile
-    (guile-for-build guile-version))
+    ;; When PULL-VERSION >= 1, produce a self-contained Guix and use Guile 2.2
+    ;; unconditionally.
+    (guile-for-build (if (>= pull-version 1)
+                         "2.2"
+                         guile-version)))
 
   (mbegin %store-monad
     (set-guile-for-build guile)
@@ -920,9 +924,11 @@ (define guile
                                #:name (string-append "guix-"
                                                      (shorten version))
                                #:pull-version pull-version
-                               #:guile-version (match guile-version
-                                                 ("2.2.2" "2.2")
-                                                 (version version))
+                               #:guile-version (if (>= pull-version 1)
+                                                   "2.2"
+                                                   (match guile-version
+                                                     ("2.2.2" "2.2")
+                                                     (version version)))
                                #:guile-for-build guile)))
       (if guix
           (lower-object guix)